Differing patterns of liver disease progression and hepatitis C virus (HCV) quasispecies evolution in children vertically coinfected with HCV and human immunodeficiency virus type 1.

نویسندگان

  • Sophie Canobio
  • Cynthia M Guilbert
  • Myriam Troesch
  • Johanne Samson
  • Mireille Lemay
  • Veronique Anne Pelletier
  • Anne-Claude Bernard-Bonnin
  • Rafal Kozielski
  • Normand Lapointe
  • Steven R Martin
  • Hugo Soudeyns
چکیده

Hepatitis C virus (HCV) quasispeciation was studied in two children vertically coinfected with HCV and human immunodeficiency virus type 1 (HIV-1). HCV quasispecies diversification and liver injury were more significant in patient C1, who was immunocompetent with anti-HIV therapy, than in patient C2, who was immunosuppressed, in consistency with modulation of HCV quasispeciation and liver injury by immunocompetence in coinfected children.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 9  شماره 

صفحات  -

تاریخ انتشار 2004